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10.1016/j.clbc.2017.05.006 19 BearH

Otis, T

F.MackeyC.et al (2018)

IGF-1 LR3 differs from endogenous IGF-1 in one critical way: the arginine substitution at position 3 prevents binding to IGF-binding proteins (IGFBPs), extending circulation time and allowing the peptide to remain bioavailable far longer than native IGF-1