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Melanocortin signaling is counterbalanced by two endogenous antagonists: agouti signaling protein (ASIP) , which blocks MC1R and MC4R in melanocytes and adipose tissue, and agouti-related peptide (AgRP) , which antagonizes MC3R and MC4R in the hypothalamus and modulates food intake
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Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II
Promotes Metabolic Health Supports metabolic health by promoting balanced enzyme activity and cellular energy processes