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Other proteins have structural or mechanical functions, such as those that form the cytoskeleton, a system of scaffolding that maintains the cell's shape

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[64] reported that a pretreatment with naringenin-7-O-glucoside increases NQO1 and ERK phosphorylation and translocation of Nrf2 to the nucleus in H9c2 cardiomyocytes

In the brain this is most likely catalyzed by pyruvate carboxylase (PC) which has a higher activity than the other enzymes capable of synthesizing oxaloacetate, i.e., malic enzyme (ME) and phosphoenolpyruvate carboxykinase ( de novo synthesis of the carbon skeleton of glutamate and GABA via glutamine requires astrocytic participation [see Ref