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The therapeutic effects of GLP-1 RAslowering blood glucose and promoting weight lossare driven by interactions with G protein-coupled receptors (GPCRs) located in the pancreas, central nervous system (CNS), and peripheral tisses (Figure 1)(Zheng et al., 2024)

The COR trials demonstrated approximately 5 to 6% weight loss beyond placebo at one year

If you take semaglutide in the evening, digestive symptoms may peak right as you attempt to fall asleep, creating a direct link between medication timing and insomnia

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GLP-1 is generally safe with most medications, but some interactions exist

To help navigate the science and available data, three ophthalmologists weighed in about how GLP-1 medications may impact vision and eye health, and why its important to visit the eye doctor for a comprehensive eye exam both before and during GLP-1 use