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Exenatide (Byetta) is initiated at 5 mcg twice daily, with a potential increase to 10 mcg twice daily after one month

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Moreover, exendin-4 inhibits NF-B activity by hindering the breakdown of IB (NF-kappa-B inhibitor alpha) in LPS-stimulated primary microglia, which reduces the activation of microglia and the generation of pro-inflammatory cytokines [113]

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