Consequently, pyridoxine significantly influences the adrenergic, serotonergic, and glutamatergic systems ( Pyridoxine may also exert a protective effect on the nervous system by regulating the glutamatergic system and thus modulating GABA and glutamate levels (60)
These features influence solubility characteristics and chromatographic retention behaviour
Kidney disease: Impaired kidney function may reduce clearance of B12 or its binding proteins
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Search was made using AJOL, DOAJ, Embase, Google Scholar, Pubmed/Pubmed Central, and Scopus databases using relevant key word searches like Cardiometabolic disorders, metabolic disorders, Reactive oxygen species, ROS, oxidative stress, lipid peroxidation, Nitrosative stress, and Antioxidants and cardiometabolic disorders
We thank an anonymous referee for pointing out the hypothesis regarding Hcy transport out of the cell to avoid toxicity
