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Virili C, Stramazzo I, Centanni M

Funding The author(s) declare no financial support was received for the research, authorship, and/or publication of this article

Inject properly: Gently pinch a fold of skin at the injection site Insert the needle at a 90-degree angle Release the pinched skin Press and hold the dose button fully Count to 6 before removing the needle (or follow the hold time in your products Instructions for Use) Dispose safely: Put the used needle in a sharps container right away without recapping

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4.3.3 Context-dependent dual role of butyrate in modulating ferroptosis via multiple signaling pathways The direct chondroprotective effects of butyrate in OA are well understood and mainly mediated by the attenuation of inflammation and matrix break down, both of which inhibit cartilage catabolism (Han et al., 2025)