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SGLT2i have shown robust effects in reducing heart failure hospitalization and slowing the progression of chronic kidney disease, while GLP-1 RAs have demonstrated superior efficacy in reducing atherothrombotic events, particularly non-fatal stroke

The other thing is that patients with diabetes may have autonomic dysfunction, thats a known complication of diabetes, so they dont regulate blood pressure well

GLP-1 medications typically come in the form of tablets or a once-weekly self-injection with a tiny, virtually painless needle while NAD treatments only come as injections

But after every attempt, I always regained the weight I lost, plus more

Wegovy HD 7.2 mg, the recently approved higher-dose version of semaglutide, shows a similar dose-dependent increase, with dysesthesia reported in roughly 22% of people at that dose compared to about 6% at the standard 2.4 mg dose

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