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Abbreviations Used 2-AG 2-arachidonoylglycerol A 2A adenosine A 2A APO A apolipoprotein A BDS botanical drug substance BMI body mass index CB1 cannabinoid receptor 1 CB2 cannabinoid receptor 2 CBC cannabichromene CBD cannabidiol CBDA cannabidiolic acid CBDV cannabidivarin CBDVA cannabidivarinic acid CBG cannabigerol CBGA cannabigerolic acid CBGV cannabigerivarin CBN cannabinol CI confidence interval CNS central nervous system CS Cannabis smoking DIO diet-induced obese DM diabetes mellitus DPCPX cyclopentyl-1,3-dipropylxanthine ECS endocannabinoid system GLUT4 glucose transporter isotype 4 HDL high-density lipoprotein I.P