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Topical application of calcipotriol primarily activates VDR signaling locally, exerting effects on keratinocyte differentiation, immune modulation, and inflammation control, with minimal systemic absorption and low risk of adverse effectsmaking it suitable for localized epidermal lesions [263]
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We have been conditioned to believe that increased intakes of saturated fat can lead to heart disease and increased cholesterol
Future studies should delve deeper into the mechanisms of NRF2 methylation and its potential therapeutic applications (Table 5)
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