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Based on how GLP-1 regimens are generally used in clinical practice, patients often notice changes along a rough pattern
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But this study challenges that narrative, showing that a hormone we thought of only as a metabolic regulator may interfere with muscle repair and growth. The findings also raise new questions about the long-term use of GLP-1based drugs, such as those prescribed for type 2 diabetes and obesity
50 Gastrointestinal Motility Disorders: Gastric and Intestinal Manifestations GLP-1 RAs reduce GI motility and prolong intestinal transit time, effects that have raised concerns regarding an increased risk of gastroparesis, intestinal obstruction, or ileus
Cummings DE, Merriam GR
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