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For maintenance or prophylactic use (such as in a patient with short-gut syndrome who cannot absorb oral vitamins well), a common regimen is 1 mL IM once weekly

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Ensure you keep the medication refrigerated as instructed and only draw it up when youre ready to inject

However, the NADPH-oxidase activity (which also uses NADPH as a cofactor) is increased (producing H 2 O 2 ) during active vitiligo, therefore increasing ROS and promoting an active competition with EAS enzymes for NADPH molecules, a molecule already reduced in active vitiligo patients (Shajil and Begum, 2006)

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