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To summarize, the present results showed that Ex-4 influences the expression of genes related to mitochondrial biogenesis, energy expenditure, and mitochondrial uncoupling, including FNDC5 coding for irisin, as well as mildly stimulating mitochondrial activity

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Stress response pathways in early embryos reflect their ability to cope with suboptimal culture conditions and environmental stresses that are inherent in assisted reproductive technology procedures [401]