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Scenario C: Biotech With Novel Delivery Platform Seeking to Maximize IP Protection A company developing a new delivery platform an LNP variant with improved endosomal escape efficiency, a new oral peptide absorption enhancer, a responsive polymer for targeted release should structure its patent portfolio with both Orange Book listing and non-listed layers

Well done everyone!

Try: 20 ounces before breakfast 20 ounces before lunch 20 ounces before dinner Additional water throughout the day Simple systems usually outperform willpower

Side effects are usually minor and short-lived

Iontophoresis: Uses a mild electrical current to push charged molecules through the skin

10.1021/acs.jmedchem.1c00104 [DOI] [PubMed] [Google Scholar] 73.National Library of Medicine