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Topical formulations have been associated with significant improvements in hyperpigmentation and skin quality, with minimal and self-resolving side effects
Duan FP, Li YS, Hu TY, Pan XQ, Ma F, Feng Y, et al
R.SeifertJ
What actually drives bioactivity is a stack of things the count never reports: the cargo (the miRNA, protein, and lipid payload that carries the signal), vesicle integrity, the source cell, purity, and a potency assay linked to mechanism of action
The transition
Chen L, Na R, McLane KD, Thompson CS, Gao J, Wang X et al (2021) Overexpression of ferroptosis defense enzyme Gpx4 retards motor neuron disease of SOD1G93A mice
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