The responsible conclusion is not: Muscle loss is a myth. It is also not: GLP-1 medications cause sarcopenia. A more accurate conclusion is: Substantial weight loss can include lean-tissue loss
Semaglutide helps control hunger and promotes feelings of fullness, so when you discontinue the medication, these effects may diminish
It is banned at all times, in-competition and out-of-competition (WADA 2026 Prohibited List)
They also improved their waist size, blood pressure, and cholesterol levels, and appeared to lose more fat than lean muscle and bone mass
some peptide-industry sources report a Pharmacy Compounding Advisory Committee review was scheduled for July 2026 that could revisit this status, but that outcome had not been independently confirmed as of this writing
VLDL responds rapidly to dietary changesfaster than any other lipid marker