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Wei Y, Wang C, Jiang B, Sun CC, Middaugh CR

Here, we describe (4 + 3) and (3 + 2) annulation strategies that quickly generate complex indole heterocycle libraries that contain novel cyclohepta and cyclopenta [ b ]indoles, respectively

31 , 503517.e508 (2020)

These studies have consistently shown significant reductions in HbA1c (a marker of long-term blood glucose control) and body weight, leading to its approval and widespread use

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