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Such toxicity has limited dose escalation and complicated combination strategies, thereby limiting its broader clinical application

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Although the precise pathogenesis of ASD remains unclear, research indicates that its etiology involves a combination of genetic factors, environmental exposures, immune dysregulation, and neurodevelopmental abnormalitiess (Guerra et al., 2024

This review aims at providing a broad view of PAIS, ranging from the molecular/cellular level to the whole organism, to provide a theoretical background and to introduce notions that could help understanding how PAIS can have both clear core features and a large set of diverse symptoms

SPONSORED CONTENT April 03, 2026 28 min listen Save Diagnosing, treating and managing hidradenitis suppurativa with Lauren Orenstein, MD In this episode, guest Lauren Orenstein, MD, MSc, discusses the challenge of diagnosing hidradenitis suppurativa, the range of therapies and pain management for patients