The most common retatrutide side effects at the 12mg dose are nausea (28%), diarrhea (24%), constipation (21%), and vomiting (17%)
For semaglutide, this could mean less impact on blood sugar regulation or weight management, potentially delaying your progress
Some people notice improved digestive regularity during this phase
5 Saxenda (liraglutide) is injected subcutaneously (under the skin) usually once daily, with or without meals
A Danish review found dementia risk lowered by 53% when Type 2 diabetes patients on GLP-1s were compared with patients on placebo, though dementia case numbers in that cohort were small
What to Know About the BALANCE Model for GLP-1s in Medicare and Medicaid and the Medicare GLP-1 Bridge Editorial Note This brief was updated on May 11, 2026 to reflect changes in the Trump administrations plans for implementation of the BALANCE Model in Medicare and an extension of the Medicare GLP-1 Bridge program through 2027