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Injection site redness can vary in severity and appearance, ranging from mild pinkish coloration to a dark red or purplish hue

If symptoms are persistent, severe, or accompanied by red flags (difficulty swallowing, unexplained weight loss beyond tirzepatide effects, vomiting), an endoscopic evaluation may be warranted

Basal energy expenditure was measured in a metabolic chamber, and did find a 97 calorie reduction per day in the intervention group

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