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Its TRIUMPH program has now reported pivotal obesity data, with the triple agonist producing the highest Phase 3 weight loss in the class and additional readouts in diabetes, cardiovascular disease, and obesity with osteoarthritis following through 2026

Cell 178 , 850866.e26 (2019)

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Large outcome trials demonstrate that GLP-1RAs reduce major adverse cardiovascular events (MACE), even in non-diabetic individuals with obesity

A recent meta-analysis associated high doses of SSRIs with greater efficacy than low or medium doses [10]

Oleuropein derivatives from olive fruit extracts reduce alpha-synuclein fibrillation and oligomer toxicity