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Nat Rev Neurosci 20 , 272281 (2019)

For additional information about this subject, you can visit the DALTCP home page at or contact the ASPE Project Officer, Jhamirah Howard, at HHS/ASPE/DALTCP, Room 424E, H.H

BMP4 was up-regulated in reactive astrocytes of SOD1 ALS rat model spinal ventral horns, and BMP4 knockdown through ASO suppressed glial activation and ameliorated the motor dysfunction (Shijo et al., 2018)

Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor

Even a low dose LPS challenge of 0.6 ng/kg body weight given intravenously can induce a profound, if transient, 25-fold and 100-fold increase in plasma IL-6 and TNF-alpha, respectively

Teredesai, Wohrmann, and Schlage 2002)