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Osteoblasts are primary cells responsible for bone development via the regulation of bone matrix synthesis and direct interaction with osteocytes and osteoclasts [19]

Ghent University Tang WW, Wang Z, Levison BS, Koeth RA, Britt EB, Fu X, Wu Y, Hazen SL (2013) Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk

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doi: 10.1007/s10753-019-01085-z 93

In neuronmicroglia co-cultures, pre-treatment of microglia with butyrate or ISRIB significantly improved SH-SY5Y neuronal viability under LPS exposure (Fig