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In Sinclairs protocols they are combined

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For most people, B12 can be taken at any time of day without affecting sleep, though morning dosing is often recommended for consistency and to address any individual sensitivity

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82,83,84 Aspartate (Asp) Aspartate metabolism Asp is an -amino acid used in protein synthesis that has an -amino group, an -carboxylic acid group, and a side-chain carboxamide

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