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To assess whether the development of insulin resistance and glucose intolerance unmasked the importance of additional DPP4-sensitive glucoregulatory substrates beyond GLP-1 and GIP, Flock et al (164) administered vildagliptin in the drinking water continuously for 8 weeks to high-fat-fed C57BL/6 wild-type and DIRKO mice

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This is the cruciferous group of vegetables, which contain high levels of sulforaphane, a phytochemical that encourages the production of glutathione