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It belongs to a class of pharmaceuticals known as sodium-glucose cotransporter-2 (SGLT2) inhibitors, which, in contrast to more conventional diabetic treatments like insulin or metformin, assist lower blood sugar levels in a unique method

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pancreatitis, gallbladder disease, and acute kidney injury are documented but less common

However, oxidative damage frequently impairs membrane integrity and transporter functionality, ultimately constraining nutrient-use efficiency

Our study also found that NRF2, GPX4 and SOD1 expression levels were higher in the neoadjuvant chemotherapy-resistant group compared to the sensitive group, further supporting our hypothesis and demonstrating the adverse effects of GSH on chemotherapy in breast cancer patients

In addition, the manufacturing facility is also inspected as part of the review process