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The difficult adaptation period concludes, side effects fade, and the medications benefits become fully apparent without the challenging tradeoffs of months 1-2

For some patients, it has brought medication and surgery closer together

N Engl J Med, 2021

This crackdown includes two rounds of warning letters to telehealth firms that sell compounded GLP-1s

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In rodent models, both GLP-1 and exendin-4 appear to influence reproductive efficiency via interaction with the hypothalamic kisspeptin (Kiss-1) system (Outeirino-Iglesias et al., 2015)