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The evaluation and management of macrocytosis has been recently reviewed in American Family Physician ( Unlike hematologic manifestations, the specific mechanism by which vitamin B 12 deficiency affects the neurologic system is unknown

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Over time, this biochemical imbalance worsens addiction symptoms, making it harder for individuals to break free from the cycle of substance dependency

doi: 10.1007/s10517-018-4227-2

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- Amphotericin B: by the increase in potassium depletion - Diuretics that produce potassium depletion (thiazides, furosemide) by increasing the potassium depletion and the risk of severe hypokalemia