They may not fully replace injectables, especially for patients requiring maximum weight reduction, but they could reshape early intervention, maintenance therapy, emerging market access, and primary care adoption
How WONDERBIOTICS Fits This Picture WONDERBIOTICS Probiotics for Weight Management was formulated around the role of the gut microbiome in metabolic health, not as a targeted intervention for GLP-1-induced constipation
Researchers in an international collaboration across the University of Ottawa Eye Institute, University of Toronto, McMaster University, and Doheny Eye Institute UCLA conducted one of the largest global studies on the topic to date
Semaglutide's evidence base is much newer and arguably more robust for the chronic weight-management context: STEP-1 (NEJM, 2021) showed mean ~15% body weight reduction at 68 weeks on semaglutide 2.4 mg weekly
Male and female heterozygous IGF-1 receptor knockout mice Igf1r +/- live 16% and 33% longer than wild-type males and females, respectively [7]
The time from finger-stick to test start should be minimised to further reduce the risk of clotting of the blood sample
