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These interventions aim to deliver targeted symptom relief directly within the joint space, with the principal agents including corticosteroids, hyaluronic acid (HA), and emerging biologics such as platelet-rich plasma (PRP) and cell-based products (Wehling et al., 2017

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Competitor Novo Nordisk is advancing therapies as well, including CagriSema , a combination of semaglutide (the active ingredient in Wegovy) and amylin