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415 of which were randomly assigned to receive varying doses of the semaglutide while the remaining participants received a placebo

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This anti-inflammatory action is mediated through several signalling pathways, including the inhibition of the nuclear factor kappa B (NF-B) pathway, contributing to the reduction of liver inflammation associated with NAFLD

The quality of life improvements - fewer hospitalizations, reduced overdoses, less suicidal ideation - represent genuine harm reduction beyond any metabolic benefits