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Semaglutide injected into lipohypertrophic tissue absorbs more slowly and unpredictably

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That is a common reason why my senior patients can't use GLP-1 medications is because they don't have insurance coverage

The downsides of microdosing GLP-1s The main downside is that you likely wont see results quite as quickly as you would with a higher dose

However, these studies excluded individuals with a history of major depression or psychiatric diseases and reported no significant differences in psychiatric outcomes between liraglutide and placebo groups