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In such disease, there will be abnormal activation of several enzymes, such as cyclooxygenase (COX)-2, glutathione (GSH) peroxidase (GPx), nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX), inducible nitric oxide synthase (iNOS), high-mobility group box 1 (HMGB1), and superoxide dismutase (SOD) also observed [7, 8]

After receiving daily injections for an average of 20 days, the subjects who received GH increased their lean body mass (which reflects muscle mass but can also include fluid mass) by an average of 4.6 pounds