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Taylor et al., 2021)

Theoretically, because Orlistat and Wegovy operate through entirely different pathwaysOrlistat reducing fat absorption and Wegovy regulating appetite and digestionthey could have a complementary effect

It preserves only the anti-inflammatory signaling fragment

Common side effects across most injected peptide therapies include: Swelling : Particularly in the lower legs or hands, known as peripheral edema

According to the Mounjaro Summary of Product Characteristics (SmPC), these two treatments do not have a known direct pharmacological interaction, as they work through entirely different mechanisms and are metabolised via separate pathways