Dr Winnett says that for patients who do not want these large ongoing monthly costs, or who are severely overweight, surgery remains the optimal option for cost and effectiveness
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85 Studies included in this review also evaluated several non-GLP-1 receptor agonists, including orlistat (8 studies), lorcaserin, phentermine, metformin, and naltrexone/bupropion aligning with their reported use in literature from Arab countries