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Metabolic disorders serve to further exacerbate the pathological progression of AD through a number of different mechanisms [76]

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39 One of the more important aspects of this disease is the chronic inflammatory and oxidative stresses that accompany the infection, which eventually contribute to the loss of CD4 (helper) T-cells, increased opportunistic infections, immuno-deficiency in general, wasting disease, and death

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This enzyme converts L-arginine into nitric oxide and L-citrulline