In pulmonary fibrosis studies using bleomycin-induced injury in mice, doses of 2.6-260 g/mL/day administered every other day from day 4-21 reduced inflammatory cell infiltration, decreased interstitial thickness, and reduced TNF- and IL-6 expression
When alcohol is metabolised, it increases oxidative stress and rapidly depletes glutathione stores in the liver
Avoid taping the syringe when removing the air before an injection
When you push bacteriostatic water directly onto the lyophilized powder at high pressure, the force can denature the peptide chains
Chemokines linked to transmigration include CCL5 (Ubogu et al., 2006), CCL2 for dendritic cells (Sagar et al., 2012), or CXCL12 for T cells and monocytes (Man et al., 2012)
While the effect of collagen V on fibril diameter is intrinsic to its structure and does not require enzymatic activity or the presence of noncollagen proteins, the mechanism by which collagen V regulates fibril size is uncertain