is glp-1 safe to use medications like Ozempic, Wegovy and Mounjaro are changing diabetes and weight management, but they aren't recommended during pregnancy or while nursing. The current recommendation stop before conception and discuss Weighing the Consumer Impacts of

This vital hormone plays several roles in the body: Regulates Blood Sugar : GLP-1 enhances insulin release, which helps regulate blood glucose levels

Memory Enhancement Improves cognitive function and supports brain health

Semaglutide for managing overweight and obesity (TA875)

Upon binding to GLP-1R, GLP-1 triggers the activation of the G protein, which stimulates adenylyl cyclase [4]

Daniel Drucker [Biomarker April 2023] 5

Dose-by-dose weight loss in Phase 2 (NEJM) Phase 2 NEJM weight loss by dose, 24 and 48 weeks Dose 1 mg 24 weeks -7.2% 48 weeks -8.7% Dose 4 mg 24 weeks -12.9% 48 weeks -17.5% Dose 8 mg 24 weeks -15.7% 48 weeks -22.8% Dose 12 mg 24 weeks -17.5% 48 weeks -24.2% Dose Placebo 24 weeks -1.6% 48 weeks -2.1% Source: Jastreboff et al., NEJM 2023