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Oxidative stress is a critical factor contributing to the age-associated decline in oocyte quality ( 2.2 Oxidative stress results in a reduction in chromosomal cohesion Chromosomal cohesion is facilitated by adherin proteins, which are established during the early stages of embryonic development ( 2.3 Oxidative stress results in aberrant spindle assembly The spindle assembly in human oocytes exhibits instability

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Daily intake of 4 to 7 g dietary vitamin B-12 is associated with steady concentrations of vitamin B-12related biomarkers in a healthy young population

These side effects are not experienced by everyone , and individual experiences can vary