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RANKL is a member of the tumor necrosis factor (TNF) family and is recognized as the only cytokine that performs a critical role in bone metabolism by regulating osteoclast formation, maintenance, and activation and is responsible for bone resorption (Weitzmann 2013)

Their mechanism involves binding to receptors located throughout the body, including in the pancreas, gastrointestinal tract, and brain regions involved in appetite regulation

Am J Physiol Endocrinol Metab 2016

This product is not intended to diagnose treat cure or prevent any disease.

Data analysis Data shown are mean standard error of the mean

Researchers examine how this endogenous peptide affects sleep latency, sleep stage distribution, cortisol/corticosterone levels, and stress-induced sleep disturbances in experimental systems focused on sleep neuroscience and stress physiology