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O uso fora das indicaes aprovadas (off-label) tambm tem gerado debates ticos, legais e de acesso

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Thus, effective digestion and biotransformation of polyphenols underpins their capacity to enhance performance, endurance, and post-exercise repair

In particular, determining when it makes sense to treat gastroesophageal reflux or perform a reflux repair plays a key role in guideline-based care for affected patients

Additionally, a history of acute pancreatitis is flagged as a relative contraindication requiring careful risk-benefit analysis by a physician