SFN mitigates TNF-a and IL-22-induced activation of inflammatory pathways and proliferation in HaCaT cells IL-22 is known to bind to the IL-22 receptor on keratinocytes, induce STAT3 phosphorylation, and promote keratinocyte proliferation [25, 26]
doi: 10.2174/092986706777452542 91 FraternaleA.ZaraC.De AngelisM.NencioniL.PalamaraA
Viana da Silva S, Haberl MG, Zhang P, Bethge P, Lemos C, Gonalves N et al (2016) Early synaptic deficits in the APP/PS1 mouse model of Alzheimers disease involve neuronal adenosine A2A receptors
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