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During the 1970s the pharmaceutical company Glaxo has poured a lot of investment into the development of CCK because it had been shown to suppress appetite in rodents

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Back Drucker, DJ, Philippe, J, Mojsov, S, et al (May 1987) 'Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line', Proceedings of the National Academy of Sciences , 84/10, 3434-8

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