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Staying at 0.25 mg for eight weeks instead of four gives your GI system twice as long to adapt before the next increase

A study estimated that 13% to 30% of patients experience long-term weight regain after surgery

In addition, the once-weekly administration schedules of long-acting GLP-1 RAs may be linked to improved adherence and persistence on medication [6]

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The extent of weight loss likely also reflects the potency of anti-inflammatory effect, and biomarkers indicative of reduced inflammation have been shown to precede wight loss in multiple trials of this drug class