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Retrieved from Evans, J., Richards, J
Kaiser Permanente
applies to the studied product in trial conditions SELECT trial (NEJM): 20% lower risk of major cardiovascular events - applies specifically to FDA-approved Wegovy in patients with established cardiovascular disease and overweight/obesity
This slows the rate of entry of nutrients into the small intestine and their subsequent absorption, thereby affecting post-prandial glucose homeostasis
It has the same proposed mechanism: turning fiber into butyrate to support natural GLP-1 production
It can influence when side effects like nausea or gastric discomfort show up during key sessions and it limits your flexibility if you need to stop before a major event or respond quickly to changes in anti-doping rules
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