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This approach produces layered responses in collagen, elastin, and extracellular matrix markers in controlled experimental settings

Luminescence measurements were performed using 475/30 nm and 535/30 nm filters with baseline measurements taken for ~3 min before addition of vehicle or peptide and reading resumed for a further 10 min

p53 controls both apoptosis and senescence by promoting p21 transcription, resulting in cell cycle arrest during DNA repair

In sepsis, pathogen-associated molecular pattern (PAMP) stimulation triggers innate immune responses, whereas damage-associated molecular pattern (DAMP) signaling promotes innate immune responses

This work was supported by the grants from Jiangsu Provincial Research Hospital (YJXYY202204-YSB38 and YJXYY202204-2-YSC12), and the Project of Jiangsu Degree and Graduated Students Education Association (JSYXHXM2023-ZYB19)