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All other solvents and reagents in this investigation were of analytical grade and used without further purification

Body-weight scaling is not straightforward: allometric differences in metabolism between a 2 kg rodent model and a 40 kg dog mean a simple g/kg extrapolation may not translate

Moreover, following systemic administration, mGIPR-Ab has access to the brain and results in weight loss comparable to central administration of mGIPR-Ab

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Ask whether other patients have reported similar concerns with the same batch

Table 4 also showed that AST and ALT concentrations increased significantly in the CT group, whereas minimal changes in ALT concentration were observed during fasting in the LC group