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(Photo by Amanda Andrade-Rhoades/The Associated Press) Anna Wysocks aha moment arrived in an Ohio amusement park, as she got ready to ride a roller coaster with her 7-year-old son: The safety bar across her lap would only click into place once

A professor of medicine at Northwestern University's Feinberg School of Medicine, he helped lead the clinical trials that brought semaglutide to market, and he spent the decades before that treating obesity with diet, behavior change, and lifestyle coaching

Two biological shifts drive this