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The top pathways based on upregulated DEGs included chemical carcinogenesis, reactive oxygen species, ribosome, and oxidative phosphorylation, among others (Fig

Consistent with these findings, whole-mount analysis of the adult mouse intestine shows Esm1 immunostaining in the peri-arterial domain of the villus capillary network, which is characterized by pronounced anti-Caveolin 1 signal and absent Endomucin expression (Supplementary Fig

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They initially screened a genome-wide collection of yeast genes and found several candidates which protected against Huntingtons related symptoms in yeast