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In addition, it can be converted to its extremely toxic metabolite NAPQI by the cytochrome P450 (CYP)2E1 enzyme

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Moreover, ajoene and allicin have a polarized bond between oxygen and one of the sulfur atoms, making these molecules more reactive compared to a simple disulfide toward nucleophilic thiol groups (Gruhlke et al

People with osteoarthritis in their fingers may experience their first gout attack in their finger joints